Gene Delivery Technologies Market Is Expected To Expand At A CAGR Of 15.1% From 2021 To 2028

 Gene Delivery Technologies Industry Overview

The global gene delivery technologies market size is expected to reach USD 7.9 billion by 2028, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 15.1% from 2021 to 2028. Technological advancements in viral vectors, a growing pipeline of advanced therapies, and a rising number of regulatory approvals for advance therapy products are some key driving forces of the market.

 

Several novel tools are being introduced for genetic alterations that have facilitated the scientific community to delineate the disease intricacies at the genomic level, leading to the emergence of novel gene delivery approaches. Furthermore, ongoing research to develop clinically relevant vectors including viral and non-viral vectors to combat chronic illnesses such as cancer, Alzheimer’s, and others through advanced therapies is spurring the market revenue.

An increase in investment and financing in the space to support the research, development, and manufacturing of various modes of gene transfer further accelerates the revenue growth. Currently, around 70% of gene and cell therapy programs are based on viral vectors leading to organic revenue growth for biological delivery technologies. The operating players are investing significantly to scale up their viral vector manufacturing capability and meet the growing demand.

Considering growing opportunities in physio-chemical gene delivery approaches, key players are making focused efforts to boost their business presence. For instance, nanoparticles have proven their efficiency as promising vehicles for clinical usage owing to their tunable morphology, and biological behaviors. Such ongoing developments in the space are anticipated to accelerate revenue growth in this market in the coming years.

 

Gene Delivery Technologies Market Segmentation

Grand View Research has segmented the global gene delivery technologies market on the basis of mode, application, method, and region:

Based on the Mode Insights, the market is segmented into Biological, Chemical, and Physical.

  • The biological vectors segment dominated the market for gene delivery technologies and accounted for the largest revenue share of 58.0% in 2020 owing to the huge success of Kymriah and Yescarta. Viral-vectors have received great attention since the approval of the first viral vector-based gene therapy products.

 

  • The lowest penetration of the physical method is their relatively lower transfection efficiency as compared to the biological and chemical methods. Low cell viability is another major shortcoming of electroporation-based physical methods. 

 

Based on the Application Insights, the market is segmented into Gene Therapy, Cell Therapy, Vaccines, and Research.

  • The gene therapy segment dominated the gene delivery technologies market and captured the maximum revenue share of 33.0% in 2020. The growing acceptance of gene-based therapies and the consequent increase in the number of clinical research initiatives have fueled the revenue generation in this segment.

 

  • The second-generation DNA vaccines exhibit the potential to induce more-potent humoral and cellular responses. This has facilitated the investigation of this approach of disease management in both therapeutic and preventative arenas. This is anticipated to drive the uptake of gene editing tools for vaccine development.

 

Based on the Method Insights, the market is segmented into Ex vivo, In vivo, and In vitro.

  • With a revenue share of 41.0%, the ex vivo method dominated the market for gene delivery technologies in 2020 owing to its several advantages such as the ability to assess transduction efficiency prior to implantation of cells back into the patient and less immunogenic responses. Also, it offers high transduction efficiency leading to its high usage in research settings.

 

  • On the contrary, although in vivo gene therapy is the preferred choice of gene transduction, this mode poses challenges in cases where highly targeted delivery is required. Errors in targeted delivery result in an immune response, thus less penetration of this segment in the market for gene delivery technologies.

 

Gene Delivery Technologies Regional Outlook

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa (MEA)

 

Key Companies Profile & Market Share Insights

The increasing interest of public and private investors in gene delivery technologies is anticipated to accelerate the entry of new players into the market. In addition, the current major players are adopting various strategic initiatives such as mergers and acquisitions, licensing, and partnering to enhance their market presence. In the past few years, the market for gene delivery technologies has witnessed notable mergers and acquisitions.

For instance, in May 2020, Merck announced the acquisition of Themis, a vaccines and immune-modulation therapies developer to expand its vaccine development capabilities for the SARS-CoV-2 vaccine program. Similarly, in May 2019, Thermo Fisher Scientific acquired Brammer Bio, a CDMO actively engaged in manufacturing viral vectors for gene therapies. In addition, end-users such as cell and gene therapy developers are engaged in strategic alliances with vector supplier for their therapy development, thereby propelling the market growth. Some of the prominent players in the gene delivery technologies market include:

  • Thermo Fisher Scientific, Inc.
  • QIAGEN
  • Horizon Discovery Group Co.
  • OriGene Technologies, Inc.
  • Oxford Biomedica
  • SignaGen Laboratories
  • Vectalys
  • Takara Bio Inc.
  • Bio-Rad Laboratories, Inc.
  • System Biosciences llc
  • Promega Corporation
  • Hoffmann-La Roche AG
  • Sirion-Biotech GmbH
  • Catalent Inc.

 

Order a free sample PDF of the Gene Delivery Technologies Market Intelligence Study, published by Grand View Research.

 

About Grand View Research

Grand View Research, U.S.-based market research and consulting company, provides syndicated as well as customized research reports and consulting services. Registered in California and headquartered in San Francisco, the company comprises over 425 analysts and consultants, adding more than 1200 market research reports to its vast database each year. These reports offer in-depth analysis on 46 industries across 25 major countries worldwide. With the help of an interactive market intelligence platform, Grand View Research Helps Fortune 500 companies and renowned academic institutes understand the global and regional business environment and gauge the opportunities that lie ahead.

 

Contact:

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Grand View Research, Inc.

Phone: 1-415-349-0058

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Email: sales@grandviewresearch.com

Web: https://www.grandviewresearch.com

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